MELIONSBROTHER

SIZE 6 X 10 TABLETS

Multi‐drug ayurvedic formulation that helps in the management of painful disorders.

• Relieves nociceptive pain (vedana‐hara) by (1) Lowering the stimulation of pain nerve endings (anti‐ nociceptive action) possibly by inhibiting prostaglandin synthesis, phospholipase A2, interleukin‐1β and interleukin‐8; (2) Blocking the pain signals in the spinal cord and brain; and (3) Binding of the acetyl and benzoyl esters to the sodium channels and thus activating the influx of sodium ions through cell membrane.

• Anti‐inflammatory (shotha‐hara)

• Jatiphal (Myristica fragrans)

  

  Jatiphal is analgesic (shula-nut), anti-inflammatory (vrana-hara), anti-rheumatic (ama-vata-hara), and modulates neuro-endocrine mechanisms (anil-apaham). It showed sedative and analgesic effects, with no harmful effects on blood pressure and ECG. With the current information, it is evident that M. fragrans has pharmacological functions including anti-inflammatory, analgesic, anti-convulsant, antibacterial, antifungal and antioxidant activities.

  Godanti (Gypsum)

  

  Godanti is an analgesic (vedna-hara) and antipyretic (jvara-hara). It is widely used for the management of headache, fever, body-ache, and other painful conditions.

  Vatsanabh (Aconitum ferox)

  

  Vatsanabh is analgesic (vedana-sthapana) and antipyretic (jvara-hara). The principal mechanism underlying the analgesic action is – the acetyl and benzoyl esters present in the diester diterpinoid alkaloids bind to the sodium channels and activate the influx of Na+ ions through cell membranes.

  Hingul (Hydrargyrum sulfuratum)

  

  Hingul is antipyretic (jvara-hara), anti-rheumatic (ama-vata-hara), anti-toxic (gara-hara), and bioavailability enhancer (yogavahi).